My Experience With Bupropion (Wellbutrin)

Large parts of the population in Western countries currently consume either alcohol, cigarettes, weed, or toxic amounts of sugar – or a combination of these. Millions of others consume amphetamines, opioids, and cocaine. These drugs provide temporary pleasure, but almost always have negative long-term consequences.

Viewed in terms of mortality, morbidity, or even life enjoyment, people would be better off if they switched to “good drugs”, namely drugs that have long-term beneficial effects on the user. In my opinion, bupropion may be such a drug.

Bupropion is a much milder (but much more sustainable) version of amphetamine. It has powerful mood-brightening effects, is stimulating, increases drive, boosts libido, decreases appetite, and has few adverse effects once the initial accommodation is over.

Bupropion is an atypical antidepressant that mainly works on the noradrenergic and dopaminergic systems while leaving the serotonergic system mostly untouched.

Bupropion is the only frequently prescribed antidepressant that does not cause weight gain, sedation, or sexual dysfunction – quite the opposite, it tends to improve energy levels and sexual function, and tends to cause weight loss. It also has a milder withdrawal than other antidepressants.

Perhaps unfortunately, bupropion is rarely used as a first-line antidepressant because many physicians assume that it worsens anxiety. Contrary to popular belief, bupropion is no more likely to worsen anxiety than SSRIs, other than perhaps during the first weeks or so. Furthermore, there is even preliminary evidence that bupropion may be an effective treatment for generalized anxiety disorder and social anxiety disorder (without depression).

For some reason, bupropion is a controlled substance in Russia.

Personal experience

A couple of years ago, I wanted to try out bupropion during a time I felt a little worse than “meh”.

The above is only a fraction of the article. This article is currently undergoing final revisions and is expected to be published within the next few weeks to months. To receive a notification upon its release, sign up for my newsletter.