Selegiline is an irreversible MAO-B inhibitor. In other words, it destroys the enzyme that breaks down dopamine and some trace amines. Selegiline was developed for the treatment of Parkinson’s disease. More recently, a transdermal patch (Emsam) was approved for the treatment of depression. Some people use selegiline as a cognitive enhancer because it elevates dopamine levels in a unique way.
Personal experience
A few years back, I went on a six-month-long journey around the world with one of my closest friends. As we were in India, I bought some selegiline because I had long been curious about its effects.
new pic sele
On the first day I took it, my friend said something that annoyed me. Instead of talking about it like I normally would, I simply followed my impulses and snapped at him in a way that is quite unlike me. Back then, I did not think much of it. But in retrospect, this should have been an early warning sign.
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