Metabolic drugs can have a powerful impact on metabolic health, which is key to longevity. Metabolic drugs affect key molecular pathways including insulin/IGF-1, mTOR, and AMPK pathways, which have all been extensively studied in the context of longevity and are key candidates for extending health span and lifespan. Nutrient-sensing pathways are presumably more important for delaying aging than reversing it.
I will now discuss a couple of these drugs in more detail and describe my experience with them as a metabolically healthy person.
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